Job Description
Project background
Advanced Patient-derived 3D Bone Organoids for In Vitro Osteoporosis Research
Fragility fractures are among the most serious consequences of impaired skeletal health in older adults, often leading to reduced mobility, loss of independence, and long-term disability. Although current standards of care provide important tools for assessing skeletal health and fracture risk, patient-specific biological responses to altered bone remodelling, mechanical loading, and inflammation remain difficult to capture in conventional assessment workflows. This is particularly relevant in osteoporosis and related age-associated bone disorders, where patients can differ substantially in bone remodelling activity, inflammatory status, bone formation capacity, osteoclast activity, and capacity for mechanoadaptation. A better understanding of these differences could support more personalised strategies for osteoporosis research and fracture preven...