Job Description
Introduction
After a heart attack, the human heart heals largely by scarring rather than true regeneration. This PhD project aims to uncover the mechanobiological rules that push cardiac tissue toward pathological fibrosis in most animal species and toward more regenerative repair in rare animal species. You will engineer and study cross-species cardiac microtissue models and quantify how defined mechanical and biochemical cues from the cellular microenvironment shape mechanobiological tissue response to injury. You will then ambitiously use these quantitative insights to build predictive, testable mechanobiological hypotheses and identify intervention points to steer microtissue repair responses toward a more regenerative outcome.
Job Description
The research will be conducted in the at Eindhoven University of Technology (TU/e) under the supervision of and Dr. Vito Conte, within the Soft Tissue Engineering and Mechanobiology (...