💼 Full-Time Position

Senior Principal AI/ML Engineer - Research Sovereign AI

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Mayo Clinic
📍 Rochester, Minnesota, United States
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Location
Rochester, United States
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Posted
April 12, 2026
Type
Full-Time
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Full-Time Opportunity: This is a permanent, full-time position with a competitive package and real career growth potential.

Job Description

Position Summary

The Senior Principal AI/ML Engineer for AI Representation & EMR Vectorization is the senior technical leader and lead scientist responsible for architecting Mayo Clinic’s unified multimodal EMR representation layer. This role defines and builds the scientific substrate used by foundational models, clinical agents, and research applications. The individual serves as a hands-on expert and player-coach, guiding technical strategy while contributing directly to model development, graph construction, and representation science. Over time, this position will build and lead a specialized team. 

Key Responsibilities

Scientific & Technical Leadership

  • Design and implement Mayo’s multimodal EMR representation AI architecture, including text, imaging, waveform, structured data, temporal sequences, and multi-visit trajectories.
  • Develop graph-based representations and knowledge graphs linking patients, events, attributes, clin...