Job Description
Topic description
The project is part of a Nexus project implying 3 partners and 3 PhD students. Partner D1 (John De Vos’ Lab) is expert in iPS cells and their differentiation into bronchial epithelium, Partner D2 (Gladys Massiera) is biophysicists experts in mucus rheology, cilia beating and microfluidics, and Partner D3 (Delphine Muriaux) is virologist expert in human viruses. The PhD students will work jointly to combine expertise and promote transdisciplinarity.
Context : The lungs, a vital organ, are constantly exposed to a multitude of environmental factors, collectively referred to as the exposome. It is not surprising that respiratory diseases such as COVID-19, chronic obstructive pulmonary disease (COPD), and asthma, are major public health concerns. However, the interactions between these exposures are complex and not yet fully understood due to the lack of a realistic in vitro model that mimics the complex structure of the airways. Organoids, ...